MARC Close

• LDR

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  20200903154003

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  181012s2018 enk o 000 engd

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  ▼a  9781527518346
  ▼q  (electronic bk.)

• 020

  ▼a  1527518345
  ▼q  (electronic bk.)

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  ▼z  9781527513778

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  ▼a  1910587
  ▼b  (N$T)

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  ▼a  (OCoLC)1056711306

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  ▼a  N$T
  ▼b  eng
  ▼c  N$T
  ▼d  248023
  ▼d  EBLCP
  ▼d  N$T
  ▼e  rda
  ▼e  pn

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  ▼a  RC346

• 082

  ▼a  616.8/047
  ▼2  23

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  ▼a  Bergantin, Leandro Bueno,
  ▼e  author.

• 245

  ▼a  The "Calcium Paradox" and its Impact on Neurological and Psychiatric Diseases
  ▼h  [electronic resource]/
  ▼d  Leandro Bueno Bergantin and Afonso Caricati-Neto.

• 250

  ▼a  Second edition.

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  ▼a  Newcastle upon Tyne:
  ▼b  Cambridge Scholars Publishing,
  ▼c  2018.

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  ▼a  1 online resource.

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  ▼a  text
  ▼b  txt
  ▼2  rdacontent

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  ▼a  computer
  ▼b  c
  ▼2  rdamedia

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  ▼a  online resource
  ▼b  cr
  ▼2  rdacarrier

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  ▼a  Intro; Table of Contents; List of Figures; List of Tables; Preface; Acknowledgements; List of Main Abbreviations; Chapter One; Chapter Two; Chapter Three; Chapter Four; Chapter Five; 5.1 Current therapies to treat neurological and psychiatric diseases; 5.1.1 Alzheimer's disease; 5.1.2 Parkinson's disease; 5.1.3 Depression; 5.1.4 Amyotrophic lateral sclerosis (ALS); 5.1.5 Huntington's disease (HD); 5.1.6 Spinal muscular atrophy (SMA); 5.1.7 Vascular dementia (VD); Chapter Six; Chapter Seven; Chapter Eight; 8.1 Ca2+ Signalling in Healthy Brains, and the Effects of Aging

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  ▼a  8.2 Amyloid -Peptide endorses Ca2+ Influx and a Ca2+- Mediated Excitotoxicity8.2.1 Presenilins; 8.3 Cytoskeletal pathology in AD and Ca2+; 8.4 Ca2+ Actions Upstream of the Amyloidogenesis; 8.5 Synapses and Ca2+; 8.6 Selectivity of the Neuronal Vulnerability in AD and Ca2+; 8.7 Improving Neuronal Ca2+ Homeostasis as a Therapeutic Approach for AD; 8.8 Reasonable mechanisms for healthy brain aging and AD; Chapter Nine; Chapter Ten; Chapter Eleven; Bibliography; About the Authors

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  ▼a  This book extends the original concept of the ""calcium paradox"" discovery, herein compiling more than 300 references in the field of calcium ion (Ca2+/cAMP) signalling pathways, neurotransmission and neurodegeneration, and neurological and psychiatric diseases. In this second edition, novel illustrations and tables (highlighting current medicines for treating these diseases, including their mechanism of action) offer improved insights into the concepts for students and clinicians. The description of other neurodegenerative diseases (Spinal muscular atrophy, Amyotrophic Lateral Sclerosis and.

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  ▼a  Online resource; title from PDF file page (EBSCO, viewed October 24, 2018).

• 650

  ▼a  Nervous system
  ▼x  Diseases
  ▼x  Pathophysiology.

• 650

  ▼a  Calcium channels.

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  ▼a  Caricati-Neto, Afonso,
  ▼e  author.

• 856

  ▼3  EBSCOhost
  ▼u  http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1910587

• 990

  ▼a  강리원

• 991

  ▼a  eBook