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  191213t20202020nyua ob 001 0 eng

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  ▼a  2019056341

• 019

  ▼a  1147894464

• 020

  ▼a  9780190080488
  ▼q  electronic book

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  ▼a  0190080485
  ▼q  electronic book

• 020

  ▼a  9780190080464
  ▼q  electronic book

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  ▼a  0190080477
  ▼q  electronic book

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  ▼a  9780190080471
  ▼q  electronic book

• 020

  ▼a  0190080469
  ▼q  electronic book

• 020

  ▼z  9780190080457
  ▼q  hardcover

• 035

  ▼a  2434578
  ▼b  (N$T)

• 035

  ▼a  (OCoLC)1131866480
  ▼z  (OCoLC)1147894464

• 040

  ▼a  DLC
  ▼b  eng
  ▼c  DLC
  ▼d  OCLCF
  ▼d  OCLCQ
  ▼d  OCLCO
  ▼d  248023
  ▼d  EBLCP
  ▼d  YDX
  ▼d  N$T
  ▼d  UBY
  ▼d  IUL
  ▼e  pn
  ▼e  rda

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  ▼a  pcc

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  ▼a  MAIN

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  ▼a  RM301.25
  ▼b  .C67 2020

• 082

  ▼a  615.1/9
  ▼2  23

• 100

  ▼a  Cordes, Eugene H.,
  ▼e  author.

• 245

  ▼a  Hallelujah moments:
  ▼b  tales of drug discovery /
  ▼c  Eugene H. Cordes.

• 250

  ▼a  Second edition.

• 260

  ▼a  New York, NY:
  ▼b  Oxford University Press,
  ▼c  2020.

• 300

  ▼a  1 online resource (xvi, 310 pages):
  ▼b  illustrations.

• 336

  ▼a  text
  ▼b  txt
  ▼2  rdacontent

• 337

  ▼a  computer
  ▼b  c
  ▼2  rdamedia

• 338

  ▼a  online resource
  ▼b  cr
  ▼2  rdacarrier

• 504

  ▼a  Includes bibliographical references and index.

• 505

  ▼a  Preface -- Previous Edition Preface -- Acknowledgments -- 1. Seduced by drug discovery -- 2. Proscar and Propecia: the Gary and Jerry show -- 3. Basic research, snake venoms, and ACE inhibitors: Ondetti, Cushman, and Patchett -- 4. HIV protease inhibitors: weapons in the war against HIV/AIDS -- 5. Statins: protection against heart attacks and strokes -- hallelujah! -- 6. The perils of Primaxin -- 7. The discovery of taxol: Wall, Horwitz, Holton -- 8. Avermectins: molecules of life battle parasites -- 9. Fludalanine: nice try but no hallelujah -- 10. Diabetes breakthroughs: Thornberry and Weber -- 11. Take it off! Take it all off! Drugs for weight reduction -- 12. The conquest of hepatitis C: telaprevir and beyond -- Appendix A: The small molecules of life: some basics of chemistry -- Appendix B: The basics of protein structure -- Appendix C: Proteins perform multiple functions: enzymes, receptors, ion channels -- Appendix D: The basics of drug discovery and development -- Appendix E: Structures of key molecules -- Notes -- Index.

• 520

  ▼a  "This work provides eleven stories of drug discovery and features the scientists who made them. The outcome of the discovery work has provided novel therapies in cancer, cardiovascular medicine, antibacterial and antiviral infectious diseases, parasitic diseases, metabolic diseases, and weight control. Each story begins with the basic biomedical science that revealed the pathway to effective drug therapy and continues with the step-by-step process that leads from insight to a product in clinical practice meeting a defined medical need. The tales feature creative problem solving by clever and dedicated scientists as they overcame roadblocks to success., hallelujah moments. Each drug discovery story reflects the interface between basic science, medicine, and drug discovery. Embedded in these tales are the societal and medical environments in which drug discovery takes place, the discovery of agents to treat HIV/AIDS, for example. Finally, a series of appendices provides basic chemical background for non-scientists"--
  ▼c  Provided by publisher.

• 588

  ▼a  Description based on online resource; title from PDF title page (Oxford Scholarship Online, viewed on August 13, 2021).

• 590

  ▼a  WorldCat record variable field(s) change: 650

• 650

  ▼a  Drug development.

• 650

  ▼a  Developmental pharmacology.

• 650

  ▼a  Drugs
  ▼x  Research.

• 650

  ▼a  Developmental pharmacology.
  ▼2  fast
  ▼0  (OCoLC)fst00891814

• 650

  ▼a  Drug development.
  ▼2  fast
  ▼0  (OCoLC)fst00898670

• 655

  ▼a  Electronic books.

• 655

  ▼a  Electronic books.

• 776

  ▼i  Print version:
  ▼a  Cordes, Eugene H.
  ▼t  Hallelujah moments.
  ▼b  Second edition.
  ▼d  New York, NY : Oxford University Press, 2020,
  ▼z  9780190080457
  ▼w  (DLC) 2019056340
  ▼w  (OCoLC)1131869166

• 856

  ▼3  EBSCOhost
  ▼u  https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2434578

• 938

  ▼a  ProQuest Ebook Central
  ▼b  EBLB
  ▼n  EBL6167681

• 938

  ▼a  EBSCOhost
  ▼b  EBSC
  ▼n  2434578

• 938

  ▼a  YBP Library Services
  ▼b  YANK
  ▼n  16711828

• 938

  ▼a  YBP Library Services
  ▼b  YANK
  ▼n  16724153

• 990

  ▼a  최영란

• 991

  ▼a  eBook

• 994

  ▼a  92
  ▼b  N$T